{"id":626,"date":"2022-02-07T13:55:48","date_gmt":"2022-02-07T13:55:48","guid":{"rendered":"https:\/\/wellai.health\/blog\/?p=626"},"modified":"2022-02-07T13:55:48","modified_gmt":"2022-02-07T13:55:48","slug":"what-is-a-gene-no-one-knows","status":"publish","type":"post","link":"https:\/\/wellai.health\/blog\/what-is-a-gene-no-one-knows\/","title":{"rendered":"What is a Gene? No One Knows."},"content":{"rendered":"

If someone tells you with confidence \u201cLet me tell you what gene is,\u201d reply with confidence, \u201cI doubt you know exactly what gene is.\u201d<\/strong><\/p>\n

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What genome science thought were the most important things for decades turned out to be the least important as we just now starting to understand the complexity of a human gene.<\/strong><\/p>\n

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In our exciting work as part of the Artificial Intelligence and Genomic Diagnostics International Working Group (WG-AIGD), we\u2019ve learned that the smartest genome researchers in the world don\u2019t know what the gene is and they don\u2019t know how it works.\u00a0 They are just opening up this whole new world, with the help of supercomputers and the AI.\u00a0 That\u2019s where WellAI\u2019s expertise comes in handy.<\/p>\n

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Did you know that plants and even mammals can re-write their DNA with RNA?\u00a0 How is that possible?\u00a0 That breaks the laws of the Central Dogma of Biology.<\/p>\n

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Well, with the help of AI, as enormous amounts of data are coming in daily, we\u2019re discovering new frontiers that could change our knowledge of biology completely<\/strong>.<\/p>\n

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The conventional concept of \u2018DNA-to-RNA-to-Protein\u2019 is not right!\u00a0 RNA can rewrite DNA, and it happens more often than you think.\u00a0 For example, we are learning that both parents can have certain DNA, but their offspring can have a different DNA.\u00a0 There are things outside of DNA that changed it.<\/p>\n

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Roderic Guido, a prominent genome scientist at the Center for Genomic Regulation in Barcelona says, \u201cThe degree of complexity we\u2019ve seen was not anticipated.\u201d<\/p>\n

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As scientists, we need to be humble.\u00a0 We need to accept the fact that without the machines and computer models it would be infinitely hard to figure out the genome complexity.<\/p>\n

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In our ongoing educational series, Daniel Satchkov, head of machine learning at WellAI, briefly talks about the gene and the ever-changing genome science.<\/strong><\/p>\n

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